Remdesivir triphosphate triethylammonium salt

Characterisation

CAS: 2725956-16-9

IUPAC Name: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile 6-triphosphate trisodium

Other names: GS-441524 triphosphate, Remdesivir metabolite, Remdesivir triphosphate metabolite, Remdesivir triphosphate triethylammonium salt

Molecular weight: 834.78 g/mol

Molecular formula: C₃₀H₆₁N₈O₁₃P₃

Storage: -20 °C, protect from light, stored under argon

All our products are lyophilized to ensure long shelf life and the best shipping conditions. We already have tens of satisfied clients across three continents.

We are also providing Remdesivir triphosphate in the form of Na⁺ salt.

Description

Remdesivir triphosphate triethylammonium salt is synthesised by Pure Chems. GS-443902 is the active triphosphate metabolite of Remdesivir with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from the Coronaviridae family. GS-443902 (GS-441524 triphosphate) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC₅₀s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively.

Remdesivir, developed by Gilead Sciences, is an adenosine prodrug that metabolizes into its active form GS-441524, which interferes with the action of viral RNA-dependent RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production.

Chemicals are distributed worldwide

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• Shipping through DHL in 48 hours. We can also arrange shipping on dry ice.
• All compounds are safely and rigorously packed
• We are sending triphosphates every Monday
• Delivery time 24 hours in Europe, 24-48 hours to USA, Canada, Asia

Payment

• We are sending the invoice the same day as the shipment
• We can modify the invoice for the academic institution so that the order can be paid from grants
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