3′,4′-Didehydro-3′-deoxyuridine triphosphate – CAS 2499590-38-2

Characterisation

CAS: 2499590-38-2, 2787607-83-2 (Et₃NH⁺ salt)

IUPAC Name: ((4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names: DdhU-TP, Ddh-U triphosphate, 3′,4′-Didehydro-3′-deoxyuridine triphosphate

Molecular weight: 466.12 g/mol

Molecular formula: C₉H₁₃N₂O₁₄P₃

InChI: InChI=1S/C9H13N2O14P3/c12-6-3-5(23-8(6)11-2-1-7(13)10-9(11)14)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-3,6,8,12H,4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17)/t6-,8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxyuridine triphosphate is a metabolite of 3′,4′-Didehydro-3′-deoxyuridine (DdhU). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

References

• WO2021133854 A1 2021-07-01
• WO2020202142 A2 2020-10-08
• WO2022123501 A1 2022-06-16

Chemicals are distributed worldwide

Buy 3′,4′-Didehydro-3′-deoxyuridine triphosphate now, and get your order in 48 hours

• Shipping through DHL in 48 hours
• All compounds are safely and rigorously packed

Payment

• We are sending the invoice on the same day as the shipment
• We are able to modify the invoice for the academic institution so that the order can be paid from the grants